Exosomal miRNAs in Heart Disease.

نویسندگان

  • Claudio Iaconetti
  • Sabato Sorrentino
  • Salvatore De Rosa
  • Ciro Indolfi
چکیده

Micro-RNAs (miRNAs) are small noncoding RNAs involved in the posttranscriptional regulation of gene expression. Exosomes have recently emerged as novel elements of intercellular communication in the cardiovascular system. Exosomal miRNAs could be key players in intercellular cross-talk, particularly during different diseases such as myocardial infarction (MI) and heart failure (HF). This review addresses the functional role played by exosomal miRNAs in heart disease and their potential use as new biomarkers.

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عنوان ژورنال:
  • Physiology

دوره 31 1  شماره 

صفحات  -

تاریخ انتشار 2016